AKAO 2018 Proxy Statement

22 CERTAIN RELATIONSHIPS AND RELATED PARTY TRANSACTIONS We describe below transactions and series of similar transactions, since January 1, 2017, to which we were a party or will be a party, in which the amount involved exceeds $120,000, and in which any of our directors, executive officers or holders of more than 5% of our common stock, or an affiliate or immediate family member thereof, had or will have a direct or indirect material interest. Warrant Exercise On August 23, 2017, a trust controlled by Mr. Wise exercised a warrant to purchase 35,363 shares of our common stock for an aggregate exercise price of $129,429 and received 35,363 shares of our common stock. Director and Executive Officer Compensation Please see “Executive Compensation” and “Director Compensation” for information regarding compensation of directors and executive officers. Executive Severance Agreements and Separation Agreements We have entered into executive severance agreements with our executive officers and separation agreements with our former executive officers. For more information regarding these agreements, see “Executive Compensation.” Director and Officer Indemnification Agreements We have entered into indemnification agreements with each of our directors and executive officers. These agreements, among other things, require us to indemnify each director (and in certain cases their related venture capital funds) and executive officer to the fullest extent permitted by Delaware law, including indemnification of expenses such as attorneys’ fees, judgments, fines and settlement amounts incurred by the director or executive officer in any action or proceeding, including any action or proceeding by or in right of us, arising out of the person’s services as a director or executive officer. Policies and Procedures for Related Party Transactions Our board of directors has adopted a written related party transaction policy setting forth the policies and procedures for the review and approval or ratification of related person transactions. This policy covers, with certain exceptions set forth in Item 404 of Regulation S-K, any transaction, arrangement or relationship, or any series of similar transactions, arrangements or relationships in which we were or are to be a participant, where the amount involved exceeds $120,000 and a related person had, has or will have a direct or indirect material interest, including, without limitation, purchases of goods or services by or from the related person or entities in which the related person has a material interest, indebtedness, guarantees of indebtedness and employment by us of a related person. As provided by our audit committee charter, our audit committee will be responsible for reviewing and approving in advance the related party transactions covered by the company’s related transaction policies and procedures.