AKAO 2018 Proxy Statement

Our board of directors recommends that you vote FOR the election of the director nominees named in Proposal No. 1 of the Proxy Statement, FOR the advisory vote to approve the compensation of our named executive officers as described in Proposal No. 2 of the Proxy Statement, for the option of EVERY YEAR as the frequency of future advisory votes on the compensation of our named executive officers as described in Proposal No. 3 of the Proxy Statement and FOR the ratification of the selection, by the audit committee of our board of directors, of Ernst & Young LLP as our independent registered public accounting firm as described in Proposal No. 4 of the Proxy Statement. By Order of the Board of Directors, /s/ Blake Wise Blake Wise Chief Executive Officer South San Francisco, California April 18, 2018