APLS 2018 Proxy Statement

Audit Committee The members of our audit committee are Alec Machiels, A. Sinclair Dunlop and Stephanie Monaghan O’Brien, and Mr. Machiels is chair of the audit committee. Our audit committee met four times during 2017. Our audit committee’s responsibilities include: • appointing, approving the compensation of, and assessing the independence of our independent registered public accounting firm; • overseeing the work of our independent registered public accounting firm, including through the receipt and consideration of reports from such firm; • reviewing and discussing with management and our independent registered public accounting firm our annual and quarterly financial statements and related disclosures; • monitoring our internal control over financial reporting, disclosure controls and procedures and code of business conduct and ethics; • overseeing our internal audit function, if any; • overseeing our risk assessment and risk management policies; • establishing procedures for the receipt and retention of accounting related complaints and concerns; • meeting independently with our internal auditing staff, if any, our independent registered public accounting firm and management; • reviewing and approving or ratifying any related person transactions; and • preparing the audit committee report required by SEC rules. All audit and non-audit services, other than de minimis non-audit services, to be provided to us by our independent registered public accounting firm must be approved in advance by our audit committee. Our board of directors has determined that Mr. Machiels is an “audit committee financial expert” as defined in applicable SEC rules and that each of the members of our audit committee possesses the financial sophistication required for audit committee members under Nasdaq rules. We believe that the composition of our audit committee meets the requirements for independence under current Nasdaq and SEC rules and regulations Compensation Committee The members of our compensation committee are Stephanie Monaghan O’Brien and Alec Machiels, and Ms. O’Brien is the chair of the compensation committee. Our compensation committee met twice during 2017. Our compensation committee’s responsibilities include: • reviewing and approving, or making recommendations to our board of directors with respect to, the compensation of our Chief Executive Officer and our other executive officers; • overseeing the evaluation of our senior executives; • overseeing and administering our cash and equity incentive plans; • reviewing and making recommendations to our board of directors with respect to director compensation and management succession planning; • reviewing and discussing annually with management our “Compensation Discussion and Analysis” disclosure report if and to the extent then required by SEC rules; and • preparing the compensation committee report if and to the extent then required by SEC rules. We believe that the composition of our compensation committee meets the requirements for independence under current Nasdaq and SEC rules and regulations. - 14 -

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